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Effects of prenatal alcohol exposure on forepaw digit length and digit ratios in rats

17 Nov 2004

Abstract excerpt

Prenatal exposure to alcohol can cause limb and digit defects. Variations in digit ratios in humans are associated with prenatal testosterone exposure. Since prenatal alcohol can reduce testosterone in rats, the effects of prenatal alcohol were measured on rat digit length. Pregnant Sprague-Dawley rats were intubated with 0 g/kg, 4 g/kg, or 6 g/kg of ethanol from Gestational Day 8 (GD8) to GD20. The 0-g/kg group...

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PMID: 15549679
DOI: 10.1002/dev.20035

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