Article
No genetic linkage or molecular evidence for involvement of the PCSK9, ARH or CYP7A1 genes in the Familial Hypercholesterolemia phenotype in a sample of Danish families without pathogenic mutations in the LDL receptor and apoB genes.
Atherosclerosis - 1 Dec 2004
Damgaard Dorte, Jensen Jesper Moeller, Larsen Mogens Lytken, Soerensen Vibeke Reiche, Jensen Henrik Kjaerulf, Gregersen Niels, Jensen Lillian Gryesten, Faergeman Ole
Abstract excerpt
A locus on chromosome 1p34.1-p32 has been linked to autosomal dominant Familial Hypercholesterolemia (FH) and is termed the third FH locus. We tested whether this third FH locus is linked to the FH phenotype in 20 Danish families, with 158 members, without pathogenic mutations in the genes, encod...
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