Article
CD4 lymphopenia as a risk factor for febrile neutropenia and early death after cytotoxic chemotherapy in adult patients with cancer.
Cancer - 1 Dec 2004
Borg Christophe, Ray-Coquard Isabelle, Philip Irene, Clapisson Gilles, Bendriss-Vermare Nathalie, Menetrier-Caux Christine, Sebban Catherine, Biron Pierre, Blay Jean-Yves
Abstract excerpt
BACKGROUND: Lymphopenia is frequently observed in patients with cancer and correlates with the risk of febrile neutropenia and early death after chemotherapy. The phenotype of the depleted lymphocyte populations was investigated in the current study. METHODS: Peripheral blood lymphocyte subsets (CD3, CD4, CD8, CD19, CD56) were quantified on Day 1 using fluorescence-activated cell sorting in a prospective study of...
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