Article
Pathogenesis of hereditary hemochromatosis.
Clinics in liver disease - 1 Nov 2004
Fleming Robert E, Britton Robert S, Waheed Abdul, Sly William S, Bacon Bruce R
Abstract excerpt
Hereditary hemochromatosis comprises several inherited disorders of iron homeostasis characterized by increased gastrointestinal iron absorpstion and resultant tissue iron deposition. The identification of HFE and other genes involved in iron metabolism has greatly expanded our understanding of hereditary hemochromatosis. Two major hypotheses have been proposed to explain the pathogenesis of HFE-related...
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