Article
Structurally distinct elements mediate internal ribosome entry within the 5'-noncoding region of a voltage-gated potassium channel mRNA.
The Journal of biological chemistry - 12 Nov 2004
Jang Gwendolyn M, Leong Louis E-C, Hoang Lily T, Wang Ping H, Gutman George A, Semler Bert L
Abstract excerpt
The approximately 1.2-kb 5'-noncoding region (5'-NCR) of mRNA species encoding mouse Kv1.4, a member of the Shaker-related subfamily of voltage-gated potassium channels, was shown to mediate internal ribosome entry in cells derived from brain, heart, and skeletal muscle, tissues known to express Kv1.4 mRNA species. We also show that the upstream approximately 1.0 kb and the downstream approximately 0.2 kb of the...
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