Article
Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison.
Cancer letters - 30 Sept 2004
Sepehr Alireza, Kamangar Farin, Abnet Christian C, Fahimi Saman, Pourshams Akram, Poustchi Hossein, Zeinali Sirous, Sotoudeh Masood, Islami Farhad, Nasrollahzadeh Dariush, Malekzadeh Reza, Taylor Philip R, Dawsey Sanford M
Abstract excerpt
The age-standardized incidence of esophageal cancer (EC) varies from 3 to >100/100,000 per year in different provinces of Iran. This striking variation of incidence is associated with differences in ethnic backgrounds, raising the possibility that genetic factors are involved in the pathogenesis of EC. We compared the frequencies of polymorphisms in ten genes that have been hypothesized to have a role in risk of...
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