Article
Description of a novel HLA-DRB1 allele found in a candidate for bone marrow transplantation.
Tissue antigens - 1 Sept 2004
Mas V, Arias M T, Fabregat V, Nomdedeu B, Serrapagès C, Vives J, Martorell J, Carreras E, Ercilla M G
Abstract excerpt
We report the identification of a new DRB1* allele in a Spanish Caucasoid family during a search for a histocompatible bone marrow donor. This novel allele, designated as DRB1*1145, differs from DRB1*1123 in one nucleotide at position 199 in exon 2 (A replacing T), leading to one amino acid change from phenylalanine (Phe) to isoleucine (Ile) at codon 67. The propositus's father had identical class II alleles but...
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