Article
RNA modulation, repair and remodeling by splice switching oligonucleotides.
Acta biochimica Polonica - 1 Jan 2004
Kole Ryszard, Williams Tiffany, Cohen Lisa
Abstract excerpt
Targeting splicing by antisense oligonucleotides allows RNA modifications that are not possible with RNA interference or other antisense techniques that destine the RNA for destruction. By changing the ratio of naturally occurring splice variants the expression of mRNA is modulated. By preventing...
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