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Cloning and characterization of the murine Vmd2 RFP-TM gene family

1 Jan 2004

Abstract excerpt

Mutations in the human vitelliform macular dystrophy type 2 (VMD2) gene are known to cause autosomal dominant Best macular dystrophy (BMD), a degenerative disorder of the central retina. VMD2, together with VMD2L1, VMD2L2 and VMD2L3, belong to a closely related gene family characterized by several transmembrane (TM) spanning helical domains and an invariant arginine, phenylalanine and proline (RFP) tripeptide...

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PMID: 15218265
DOI: 10.1159/000078016

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