Article
Drosophila acetylcholinesterase: characterization of different mutants resistant to insecticides.
Biochemical genetics - 1 Feb 1992
Pralavorio M, Fournier D
Abstract excerpt
Selection of field populations originating from several countries allowed us to isolate 13 strains of Drosophila melanogaster resistant to parathion. In vitro studies of acetylcholinesterase inhibition by paraoxon have been carried out on purified enzymes: most of the resistant strains harbor an altered acetylcholinesterase. Enzymes with higher resistance levels have been characterized with respect to their...
Topics
- Acetylcholinesterase
- Alleles
- Animals
- Catalysis
- Cholinesterase Inhibitors
- Drosophila melanogaster
- Drug Resistance
- Female
- Mutation
- Parathion
- Species Specificity
