Article
Cardiovascular autonomic regulation in patients with 3243A > G mitochondrial DNA mutation.
Annals of medicine - 1 Jan 2004
Majamaa-Voltti Kirsi, Majamaa Kari, Peuhkurinen Keijo, Mäkikallio Timo H, Huikuri Heikki V
Abstract excerpt
BACKGROUND: Patients with the 3243A > G mutation in mitochondrial DNA (mtDNA) have an increased risk for cardiovascular morbidity and mortality. The function of the autonomic nervous system has not been evaluated in these patients. PATIENTS AND METHODS: Indices of 24-hour heart rate variability (HRV) and baroreflex sensitivity (BRS) were measured in 28 patients with 3243A > G. The results were compared to...
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