Article
Contribution of gelatinase, serine protease, and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis.
Infection and immunity - 1 Jun 2004
Engelbert Michael, Mylonakis Eleftherios, Ausubel Frederick M, Calderwood Stephen B, Gilmore Michael S
Abstract excerpt
Gelatinase and serine protease were found to contribute in concert to pathogenesis in a rabbit model of endophthalmitis. However, a mutant defective in the fsr regulator was observed to be more attenuated than a mutant rendered defective in the expression of gelatinase and serine protease as the result of a polar transposon insertion into the former. This increased attenuation suggests that there are possible...
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