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Article

A novel mutation, Ser143Pro, in the lamin A/C gene is common in finnish patients with familial dilated cardiomyopathy.

European heart journal - 1 May 2004

Kärkkäinen Satu, Heliö Tiina, Miettinen Raija, Tuomainen Petri, Peltola Paula, Rummukainen Juha, Ylitalo Kari, Kaartinen Maija, Kuusisto Johanna, Toivonen Lauri, Nieminen Markku S, Laakso Markku, Peuhkurinen Keijo

Abstract excerpt

AIMS: The mutations most frequently associated with dilated cardiomyopathy (DCM) have been reported in the lamin A/C gene. The role of variants of the lamin A/C gene was investigated in patients with DCM from eastern and southern Finland. METHODS AND RESULTS: All 12 exons of the lamin A/C gene were screened in 18 well-characterised familial DCM patients from eastern and southern Finland and in 72 sporadic DCM...

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Identifiers

PMID: 15140538
DOI: 10.1016/j.ehj.2004.01.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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