Article
Therapeutic response to pentoxifylline and its active metabolites in dogs with familial canine dermatomyositis.
Veterinary therapeutics : research in applied veterinary medicine - 1 Jan 2003
Rees Christine A, Boothe Dawn M
Abstract excerpt
Ten dogs diagnosed with familial canine dermatomyositis based on clinical findings and skin biopsy results were treated PO with pentoxifylline (25 mg/kg twice daily) for 3 months. Blood and urine samples were collected biweekly for complete blood counts, serum chemistries, and urinalysis. Additionally, serum was analyzed for pentoxifylline and its two primary metabolites (metabolites 1 [M1] and 5 [M5]); physical...
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