Mean d(2) and divergence time: transformations and standardizations.

doi:10.1093/jhered/esh021

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Article

Mean d(2) and divergence time: transformations and standardizations.

The Journal of heredity - 1 Jan 2000

Neff B D

Abstract excerpt

The fitness consequences of inbreeding and outbreeding have intrigued biologists for a long time. Recently a measure of relatedness of parental haplotypes has been proposed called mean d(2). This measure is based on a stepwise mutational process and therefore is tailored to microsatellite genetic markers. Theoretical work suggests that mean d(2) typically is less suited for measuring fitness consequences due to...

Topics

Computer Simulation
Genetic Carrier Screening
Genetic Variation
Genetics, Population
Haplotypes
Inbreeding
Models, Genetic
Mutation
Selection, Genetic

Source

Open in PubMed

Identifiers

PMID: 15073233
DOI: 10.1093/jhered/esh021

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