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Article

Correlation of major cytogenetic response with a pharmacogenetic marker in chronic myeloid leukemia patients treated with imatinib (STI571).

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2004

Dressman Marlene A, Malinowski Rachel, McLean Lee Anne, Gathmann Insa, Capdeville Renaud, Hensley Martee, Polymeropoulos Mihael H

Abstract excerpt

PURPOSE: Imatinib, an inhibitor of the Bcr-Abl tyrosine kinase, is indicated for the treatment of patients with Philadelphia chromosome-positive chronic myeloid leukemia. We examined genotypes from patients enrolled in the International Randomized Study of IFN-alpha versus STI571 in an attempt to identify factors that associate with cytogenetic response. EXPERIMENTAL DESIGN: Sixty-eight polymorphic loci in 26...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15073101
DOI: 10.1158/1078-0432.ccr-0785-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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