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Article

Allelic variants in genes associated with hereditary periodic fever syndromes as susceptibility factors for reactive systemic AA amyloidosis.

Genes and immunity - 1 Jun 2004

Aganna E, Hawkins P N, Ozen S, Pettersson T, Bybee A, McKee S A, Lachmann H J, Karenko L, Ranki A, Bakkaloglu A, Besbas N, Topaloglu R, Hoffman H M, Hitman G A, Woo P, McDermott M F

Abstract excerpt

We investigated the hypothesis that low-penetrance mutations in genes (TNFRSF1A, MEFV and NALP3/CIAS1) associated with hereditary periodic fever syndromes (HPFs) might be risk factors for AA amyloidosis among patients with chronic inflammatory disorders, including rheumatoid arthritis (RA), juven...

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Source

Identifiers

PMID: 15071491
DOI: 10.1038/sj.gene.6364070

Genes

MEFV
TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15071491-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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