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Article

Renal AA amyloidosis associated with a TRAPS-like autoinflammatory phenotype and TNFRSF1A R92Q variant in adulthood.

Acta clinica Belgica - 1 Oct 2026

Cetin Taha Enes, Haliloglu Serhat, Akcay Omer Faruk, Helvaci Ozant, Guz Galip

Abstract excerpt

BACKGROUND: Tumor necrosis factor receptor-associated periodic fever syndrome (TRAPS) is a rare monogenic autoinflammatory disorder typically presenting with recurrent febrile attacks. However, adult-onset cases without classical inflammatory symptoms may remain unrecognized and can present with organ-dominant manifestations. AA amyloidosis represents a severe complication of chronic inflammation and may be the...

Read the complete abstract on PubMed

Topics

Humans
Male
Middle Aged
Hereditary Autoinflammatory Diseases
Amyloidosis
Receptors, Tumor Necrosis Factor, Type I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Phenotype

Fatal Outcome

Kidney Failure, Chronic

Serum Amyloid A Protein

Source

Identifiers

PMID: 42409418
DOI: 10.1080/17843286.2026.2700510

Genes

TNFRSF1A

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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