Article
Attitudes toward preventive oophorectomy among BRCA1 mutation carriers in Poland.
European journal of gynaecological oncology - 1 Jan 2004
Menkiszak J, Rzepka-Górska I, Górski B, Gronwald J, Byrski T, Huzarski T, Jakubowska A, Metcalfe K A, Narod S A, Lubiński J
Abstract excerpt
Currently genetic testing for BRCA1 and BRCA2 susceptibility genes is performed throughout Europe and North America. In Poland three founder mutations in BRCA1 account for 14% of all invasive ovarian cancers and oophorectomy is frequently recommended to mutation carriers as a preventive measure. The purpose of the present study was to evaluate patient acceptance of the recommendation for prophylactic oophorectomy...
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