Article
Trisomy 4 as the sole karyotypic abnormality in a case of acute biphenotypic leukemia with T-lineage markers in minimally differentiated acute myelocytic leukemia.
Cancer genetics and cytogenetics - 1 Apr 2004
Al-Qurashi Fat-hia, Owaidah Tarek, Iqbal Mohammed A, Aljurf Mahmoud
Abstract excerpt
We report an unusual case of acute biphenotypic leukemia with trisomy 4. A 22-year-old woman presented with acute leukemia characterized by the presence of two cell populations (prothymocytic and myeloblastic). The leukemic cells were resistant to standard induction chemotherapy and were cleared from the bone marrow only after a salvage chemotherapy regimen. To our knowledge, this is the fourth reported case of...
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