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Article

Pesticide mixtures potentiate the toxicity in murine thymocytes.

Toxicology - 15 Mar 2004

Olgun Selen, Gogal Robert M, Adeshina Femi, Choudhury Harlal, Misra Hara P

Abstract excerpt

The immunotoxic risks of multiple pesticide exposure were evaluated. C57BL/6 mouse thymocytes were exposed to lindane, malathion, and permethrin, either separately or in mixtures of two pesticides, in vitro. These pesticide exposures caused both apoptotic and necrotic cell death in thymocytes as evaluated by flow cytometric analysis in combination with 7-aminoactinomycin-D (7-AAD), Annexin-V/propidium iodide (PI)...

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Identifiers

PMID: 15036745
DOI: 10.1016/j.tox.2003.09.007

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