Article
Positive directional selection in the proline-rich antigen (PRA) gene among the human pathogenic fungi Coccidioides immitis, C. posadasii and their closest relatives.
Molecular biology and evolution - 1 Jun 2004
Johannesson Hanna, Vidal Pilar, Guarro Josep, Herr Roger A, Cole Garry T, Taylor John W
Abstract excerpt
In this study, we investigate the possibility of selection acting on the proline-rich antigen (PRA) gene in natural populations of the two human pathogens, Coccidioides immitis and Coccidioides posadasii, and three of their close relatives, Chrysosporium lucknowense, Chrysosporium queenslandicum, and Uncinocarpus reesii. We addressed the following questions: Is diversifying selection acting on PRA in the...
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