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Article

Antisense RNA targeting of primase interferes with bacteriophage replication in Streptococcus thermophilus.

Applied and environmental microbiology - 1 Mar 2004

Sturino Joseph M, Klaenhammer Todd R

Abstract excerpt

The putative primase gene and other genes associated with the Sfi21-prototype genome replication module are highly conserved in Streptococcus thermophilus bacteriophages. Expression of antisense RNAs complementary to the putative primase gene (pri3.1) from S. thermophilus phage kappa 3 provided significant protection from kappa 3 and two other Sfi21-type phages. Expression of pri3.10-AS, an antisense RNA that...

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Share to DNA Primase
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Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15006799
DOI: 10.1128/AEM.70.3.1735-1743.2004
PMCID: PMC368297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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