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Norovirus Capture with Histo-Blood Group Antigens Reveals Novel Virus-Ligand Interactions

27 Feb 2004

Abstract excerpt

Noroviruses are genetically diverse, uncultivable, positive-sense RNA viruses and are the most common cause of epidemic acute gastroenteritis in humans in the United States. Recent studies of norovirus attachment in vitro by using recombinant virus-like particles (VLPs) suggest that various norovirus strains exhibit different patterns of attachment to ABH histo-blood group antigens, which are carbohydrate...

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PMID: 14990722
DOI: 10.1128/jvi.78.6.3035-3045.2004

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