Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acute myeloid leukaemia with t(8;21) associated with "occult" mastocytosis. Report of an unusual case and review of the literature.

Journal of clinical pathology - 1 Mar 2004

Bernd H-W, Sotlar K, Lorenzen J, Osieka R, Fabry U, Valent P, Horny H-P

Abstract excerpt

Approximately 20% of patients with systemic mastocytosis (SM) have an associated haematological, clonal, non-mast cell lineage disease, and most exhibit an associated myelogenous neoplasm. This report describes a 48 year old man with acute myeloid leukaemia (AML) and a type t(8;21) cytogenetic abnormality. Associated bone marrow mastocytosis (a defined subtype of SM) was only detected after successful...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Mast Cells

Share to Mastocytosis

Share to Polymerase Chain Reaction

Share to Proto-Oncogene Proteins c-kit

Share to Receptors, Interleukin-2

Source

Open in PubMed Open full text

Identifiers

PMID: 14990611
DOI: 10.1136/jcp.2003.012864
PMCID: PMC1770248

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acute myeloid leukaemia with t(8;21) associated with "occult" mastocytosis. Report of an unusual case and review of the literature.PMID 14990611Read ↗

Systemic mastocytosis with associated clonal hematological non-mast-cell lineage disease: analysis of clinicopathologic features and activating c-kit mutations.Semantic proximity Read ↗

Mastocytosis: state of the art.Semantic proximity Read ↗

Systemic mastocytosis with associated clonal hematologic nonmast cell lineage disease: a clinicopathologic review.Semantic proximity Read ↗

Systemic mastocytosis: progressive evolution of an occult disease into fatal mast cell leukemia: unique findings on an unusual hematological neoplasm.Semantic proximity Read ↗

Unresponsive Systemic Mastocytosis in a Young AML With RUNX1::RUNX1T1 Fusion With Rare KIT c.1255_1257delGAC Mutation: A Clinical Deadlock.Semantic proximity Read ↗

Diagnosis and management of mastocytosis: an emerging challenge in applied hematology.Semantic proximity Read ↗

Cytogenetic abnormalities in systemic mastocytosis: WHO subcategory-specific incidence and prognostic impact among 348 informative cases.Semantic proximity Read ↗

A multicenter retrospective comparison between systemic mastocytosis with t(8;21) AML and KIT mutant t(8;21) AML.Semantic proximity Read ↗

[Neoplastic mastocytosis evolving from a poor prognosis acute myeloid leukemia].Semantic proximity Read ↗

Neoplastic mast cells in systemic mastocytosis associated with t(8;21) acute myeloid leukemia are derived from the leukemic cloneSemantic proximity Read ↗

A case of aleukemic mast cell leukemia with an underlying myeloproliferative neoplasm: Morphological and molecular characteristics of a highly aggressive disease.Semantic proximity Read ↗

De novo mast cell leukemia without CD25 expression and KIT mutations: a rare case report in a 13-year-old child.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.