Article
Identification of a new HLA-DRB1 allele, HLA-DRB1*0436.
Tissue antigens - 1 Mar 2004
Chu C C, Lee H L, Lin M
Abstract excerpt
Anovel allele, HLA-DRB1*0436, was identified in a Taiwan indigenous individual by sequence-based typing. DRB1*0436 was identical to DRB1*0403 in exon2 but differed at codons 67-74 with five nucleotide substitutions. This corresponded to three amino acid changes within the P4 peptide-binding pocket of the DR molecule. These substitutions constitute a motif that is also seen in other DRB1*11 alleles. It is possible...
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