Article
A different amyloid formation mechanism: de novo oculoleptomeningeal amyloid deposits after liver transplantation.
Transplantation - 15 Feb 2004
Ando Yukio, Terazaki Hisayasu, Nakamura Masaaki, Ando Eiko, Haraoka Katsuki, Yamashita Taro, Ueda Mitsuharu, Okabe Hiroaki, Sasaki Yutaka, Tanihara Hidenobu, Uchino Makoto, Inomata Yukihiro
Abstract excerpt
BACKGROUND: Liver transplantation has served as a treatment for patients with familial amyloidotic polyneuropathy (FAP) because variant transthyretin (TTR), the pathogenic protein of FAP, is predominantly produced by the liver. However, the effect on amyloid formation of TTR that is synthesised by the retina and the choroid plexus remains to be elucidated in FAP patients with liver transplants. OBJECTIVE: To...
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