Article
MMP-9 polymorphisms are not associated with spontaneous cervical artery dissection.
Stroke - 1 Mar 2004
Wagner Simone, Kluge Britta, Koziol James A, Grau Armin J, Grond-Ginsbach Caspar
Abstract excerpt
BACKGROUND AND PURPOSE: Cervical artery dissection (CAD) is a common cause of ischemic stroke in young adults. Alteration in the structure of the vascular extracellular matrix has been described in CAD. Matrix metalloproteinases (MMPs) degrade extracellular matrix proteins and can lead to vascular damage. METHODS: We tested 2 different MMP-9 DNA polymorphisms, a CA repeat and a cytosine to thymidine transition in...
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