Article
Acetyl-L-carnitine has a neuromodulatory influence on neuronal phenotypes during early embryogenesis in the chick embryo.
Brain research. Developmental brain research - 18 Dec 1992
Kentroti S, Ramacci M T, Vernadakis A
Abstract excerpt
Studies from this laboratory and others have demonstrated that neuroblasts in early embryogenesis exhibit a high degree of plasticity with respect to neurotransmitter phenotype. The critical period within which these neuroblasts are sensitive to the effects of endogenous neurotrophins has been defined as 1-3 days of development in the chick embryo. In this study, we examined the influence of acetyl-L-carnitine...
Topics
- Acetylcarnitine
- Animals
- Brain
- Cell Differentiation
- Cell Division
- Chick Embryo
- Choline O-Acetyltransferase
- Glutamate Decarboxylase
- Nerve Growth Factors
- Neurons
- Phenotype