Article
The Lewis blood group--a new genetic marker of ischaemic heart disease.
Journal of internal medicine - 1 Dec 1992
Hein H O, Sørensen H, Suadicani P, Gyntelberg F
Abstract excerpt
In a cohort of 3383 men aged 53 to 74 in the Copenhagen Male Study we investigated the association between ischaemic heart disease (IHD) and the Lewis blood group, assigned to chromosome 19. Among men with the Le(a-b-) phenotype, 8% had a history of non-fatal myocardial infarction, among others the frequency was 4%. The corresponding odds ratio was (95% confidence interval: CI) 1.9 (1.2-3.0) P < 0.01, men with...
Topics
- Adult
- Chromosomes, Human, Pair 19
- Denmark
- Genetic Markers
- Humans
- Incidence
- Lewis Blood Group Antigens
- Male
- Middle Aged
- Myocardial Ischemia
- Phenotype
- Prevalence
