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Article

[Biallelic inactivation of the p16-Gen in a metachronous triple carcinoma in the oropharyngeal region].

Laryngo- rhino- otologie - 1 Jan 2004

Motsch C, Giers A, Boltze C, Evert M, Freigang B, Roessner A, Schneider-Stock R

Abstract excerpt

AIMS: Recent studies have shown that most Dutch families with atypical multiple-mole melanoma (FAMMM) have a 19-bp deletion (p16-Leiden) in exon 2 of the p16 gene. Apart from reports on metachronous pancreatic tumors, other cancer types have never been described in such families. Due to heterozyg...

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Share to Carcinoma, Squamous Cell
Share to Cyclin-Dependent Kinase Inhibitor p16
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14740307
DOI: 10.1055/s-2004-814111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14740307-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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[Biallelic inactivation of the p16-Gen in a metachronous triple carcinoma in the oropharyngeal region].PMID 14740307Read ↗

Multiple melanomas after treatment for Hodgkin lymphoma in a non-Dutch p16-Leiden mutation carrier with 2 MC1R high-risk variants.Semantic proximity Read ↗

Development of esophageal squamous cell cancer in patients with FAMMM syndrome: Two clinical reports.Semantic proximity Read ↗

Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 p16LeidenSemantic proximity Read ↗

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Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion ofp16 (p16-Leiden)Semantic proximity Read ↗

Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden).Semantic proximity Read ↗

Risk of multiple pancreatic cancers in CDKN2A-p16-Leiden mutation carriers.Semantic proximity Read ↗

A locus linked to p16 modifies melanoma risk in Dutch familial atypical multiple mole melanoma (FAMMM) syndrome families.Semantic proximity Read ↗

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