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Article

Mutation analysis of the Nijmegen breakage syndrome gene (NBS1) in nineteen patients with acute myeloid leukemia with complex karyotypes.

Leukemia & lymphoma - 1 Nov 2003

Varon Raymonda, Schoch Claudia, Reis André, Hiddemann Wolfgang C, Sperling Karl, Schnittger Susanne

Abstract excerpt

The chromosomal instability disorder Nijmegen Breakage Syndrome (NBS) is caused by germ line mutations in the NBS1 gene. It is associated with immune deficiency, cellular hypersensitivity to ionizing radiation, and high susceptibility to lymphoid malignancies due to a defect in DNA double strand...

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Source

Identifiers

PMID: 14738145
DOI: 10.1080/1042819031000099724

Genes

MRE11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14738145-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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