Article
Role of exopolysaccharide, the rugose phenotype and VpsR in the pathogenesis of epidemic Vibrio cholerae.
FEMS microbiology letters - 15 Jan 2004
Rashid Mohammed H, Rajanna Chythanya, Zhang Dalin, Pasquale Vincenzo, Magder Laurence S, Ali Afsar, Dumontet Stefano, Karaolis David K R
Abstract excerpt
Vibrio cholerae, the causative agent of cholera can produce an exopolysaccharide (EPS). Some strains can also phenotypically switch from a smooth to a 'rugose' phenotype characterized by small wrinkled colonies, overproduction of EPS, increased biofilm formation in vitro and increased resistance to various stressful conditions. High frequency switching to the rugose phenotype is more common in epidemic strains...
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