Article
A mutant form of the Neisseria gonorrhoeae pilus secretin protein PilQ allows increased entry of heme and antimicrobial compounds.
Journal of bacteriology - 1 Feb 2004
Chen Ching-ju, Tobiason Deborah M, Thomas Christopher E, Shafer William M, Seifert H Steven, Sparling P Frederick
Abstract excerpt
A spontaneous point mutation in pilQ (pilQ1) resulted in phenotypic suppression of a hemoglobin (Hb) receptor mutant (hpuAB mutant), allowing gonococci to grow on Hb as the sole source of iron. PilQ, formerly designated OMP-MC, is a member of the secretin family of proteins located in the outer m...
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