Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Warfarin skin necrosis associated with protein S deficiency and a mutation in the methylenetetrahydrofolate reductase gene.

Clinical and experimental dermatology - 1 Jan 2004

Byrne J S, Abdul Razak A R, Patchett S, Murphy G M

Abstract excerpt

The use of warfarin is rarely complicated by skin necrosis. We describe a 50-year-old woman who presented with a left leg deep venous thrombosis and subsequent pulmonary embolism. She was initially anticoagulated with low-molecular weight heparin and subsequently warfarin. Within 4 days abdominal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticoagulants
Share to Drug Eruptions
Share to Leg

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Necrosis

Share to Protein S Deficiency

Share to Venous Thrombosis

Share to Warfarin

Source

Identifiers

PMID: 14723717
DOI: 10.1111/j.1365-2230.2004.01443.x

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14723717-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Warfarin skin necrosis associated with protein S deficiency and a mutation in the methylenetetrahydrofolate reductase gene.PMID 14723717Read ↗

Factor V Leiden mutation in a patient with warfarin-associated skin necrosis.Semantic proximity Read ↗

Cutaneous necrosis revealing the coexistence of an antiphospholipid syndrome with acquired protein S deficiency, factor V Leiden and hyperhomocysteinemia.Semantic proximity Read ↗

Leg ulcers associated with factor V Leiden and prothrombin G20210A and methyltetrahydrofolate reductase mutations: successful treatment with warfarin.Semantic proximity Read ↗

A fatal case of enoxaparin induced skin necrosis and thrombophilia.Semantic proximity Read ↗

Severe digital necrosis in an elderly patient with heterozygous factor V Leiden mutation.Semantic proximity Read ↗

A case of livedoid vasculopathy associated with factor V Leiden mutation: successful treatment with oral warfarin.Semantic proximity Read ↗

Rebuttal to massive skin necrosis associated to the prothrombin gene G20210A mutation.Semantic proximity Read ↗

Activated protein C concentrate treatment for skin necrosis under warfarin treatment in severe genetic protein C deficiency combined with prothrombin mutation and factor V Leiden.Semantic proximity Read ↗

Is the coexistence of mutations in the genes of factor V and MTHFR a predisposing factor for massive skin necrosis due to loxoscelism?Semantic proximity Read ↗

Adult purpura fulminans and digital necrosis associated with sepsis and the factor V mutation.Semantic proximity Read ↗

THE METHYLENE TETRAHYDROFOLATE REDUCTASE (C677T) MUTATION AS A POTENTIAL RISK FACTOR FOR AVASCULAR NECROSIS IN SICKLE CELL DISEASESemantic proximity Read ↗

A boy with cutaneous necrosis occurring during treatment with levamisole.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.