Article
Menstrual effluent induces epithelial-mesenchymal transitions in mesothelial cells.
Human reproduction (Oxford, England) - 1 Jan 2004
Demir A Y, Groothuis P G, Nap A W, Punyadeera C, de Goeij A F P M, Evers J L H, Dunselman G A J
Abstract excerpt
BACKGROUND: Menstrual effluent affects mesothelial cell (MC) morphology. We evaluated whether these changes were consistent with epithelial-mesenchymal transitions (EMT). METHODS: Monolayer cultures of MC were incubated overnight in conditioned media, prepared from cells isolated form menstrual effluent, with or without kinase and ATP inhibitors. Changes in cell morphology were monitored using time-lapse video...
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