Article
Identification of novel genes involved in congenital hypothyroidism using serial analysis of gene expression.
Hormone research - 1 Jan 2003
Moreno José C
Abstract excerpt
Part of the molecular basis of congenital hypothyroidism (CH) has been elucidated by the identification of molecular defects in pituitary- and thyroid-specific genes in patients with various subtypes of hypothyroidism. So far identified genetic defects only explain a small proportion of cases of hypothyroidism. Thus novel research strategies are required to isolate more tissue-specific genes involved in the...
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