Article
Typing of Mycobacterium tuberculosis strains resistant to rifampicin and isoniazid by molecular biological methods.
Bulletin of experimental biology and medicine - 1 Sept 2003
Skotnikova O I, Nosova E Yu, Markova O V, Irtuganova O A, Krudu V N, Ginda S S, Golishcheva O V, Biryukova M N, Strel'tsova E N, Kalyanina O V, Litvinov V I, Moroz A M, Lapa S A, Gryadunov D A, Mikhailovich V M
Abstract excerpt
Mutations in the rpoB, katG, inhA, oxyR/ahpC genes in rifampicin- and isoniazid-resistant M. tuberculosis strains isolated from residents of Moscow, Astrakhan', and Moldova Republic were studied by molecular biological methods (heteroduplex analysis, single strand conformational polymorphism, biochips). Twenty-five combinations of mutations were detected. Some differences in the type distribution of detected...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.