Article
Phosphofructokinase muscle-specific isoform requires caveolin-3 expression for plasma membrane recruitment and caveolar targeting: implications for the pathogenesis of caveolin-related muscle diseases.
The American journal of pathology - 1 Dec 2003
Sotgia Federica, Bonuccelli Gloria, Minetti Carlo, Woodman Scott E, Capozza Franco, Kemp Robert G, Scherer Philipp E, Lisanti Michael P
Abstract excerpt
Previous co-immunoprecipitation studies have shown that endogenous PFK-M (phosphofructokinase, muscle-specific isoform) associates with caveolin (Cav)-3 under certain metabolic conditions. However, it remains unknown whether Cav-3 expression is required for the plasma membrane recruitment and cav...
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