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Article

On the relation between fluctuation and response in biological systems.

Proceedings of the National Academy of Sciences of the United States of America - 25 Nov 2003

Sato Katsuhiko, Ito Yoichiro, Yomo Tetsuya, Kaneko Kunihiko

Abstract excerpt

A general relationship between fluctuation and response in a biological system is presented. The fluctuation is given by the variance of some quantity, whereas the response is given as the average change of that quantity for a given parameter change. We propose a relationship where the two are proportional, in a similar way to the fluctuation-dissipation theorem in physics. By studying an evolution experiment...

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Identifiers

PMID: 14615583
DOI: 10.1073/pnas.2334996100
PMCID: PMC283550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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