Article
Glancing behind virus load variation in HIV-1 infection.
Trends in microbiology - 1 Nov 2003
Bonhoeffer Sebastian, Funk Georg A, Günthard Huldrych F, Fischer Marek, Müller Viktor
Abstract excerpt
Although the steady-state virus load during HIV-1 infection is remarkably stable within a patient, it displays variation over several orders of magnitude between patients. Despite intensive research, the host and virus factors that are responsible for the observed variation remain poorly understood. Comparison of model predictions with clinical data suggests that most of the variation in steady-state virus load...
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