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Article

Correlation between metastatic potential and variants from colorectal tumor cell line HT-29.

World journal of gastroenterology - 1 Nov 2003

Wang Min, Vogel Ilka, Kalthoff Holger

Abstract excerpt

AIM: To evaluate the relationship between uPA, PAI-1, CEA, PI3K and metastatic potential in three colorectal tumor cell lines. METHODS: Metastatic model in nude rats was established by variants HT-29c and HT-29d cell lines and the metastatic potential of two tumor cell variants was compared. Urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) were determined using ELISA...

Topics

Adenocarcinoma
Animals
Carcinoembryonic Antigen
Cell Line, Tumor
Colorectal Neoplasms
Disease Models, Animal
Male
Neoplasm Transplantation
Phenotype
Phosphatidylinositol 3-Kinases
Plasminogen Activator Inhibitor 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Rats, Nude

Urokinase-Type Plasminogen Activator

Source

Open in PubMed Open full text

Identifiers

PMID: 14606113
DOI: 10.3748/wjg.v9.i11.2627
PMCID: PMC4656557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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