Article
A randomized, double-blind, placebo-controlled trial of TMC125 as 7-day monotherapy in antiretroviral naive, HIV-1 infected subjects.
AIDS (London, England) - 21 Nov 2003
Gruzdev Boris, Rakhmanova Aza, Doubovskaya Ekaterina, Yakovlev Alexey, Peeters Monika, Rinehart Alex, de Dier Karin, Baede-Van Dijk Patricia, Parys Wim, van 't Klooster Gerben
Abstract excerpt
OBJECTIVE: To evaluate antiviral activity, tolerability, safety and pharmacokinetics of treatment with TMC125 (a non-nucleoside reverse transcriptase inhibitor), 900 mg twice daily for 7 days. DESIGN: Randomized, double-blind, placebo-controlled, phase IIA clinical trial. SETTING: Two hospital cl...
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