Article
MLV/HIV-pseudotyped vectors: a new treatment option for cutaneous T cell lymphomas.
Molecular therapy : the journal of the American Society of Gene Therapy - 1 Nov 2003
Thaler Sonja, Burger Angelika M, Schulz Thomas, Schnierle Barbara S
Abstract excerpt
Cutaneous T cell lymphomas (CTCLs) are lymphoproliferative disorders involving the skin. Malignant cells have a CD4+ T-helper phenotype and are found in early stages of the disease in plaques and cutaneous tumors. MLV/HIV-pseudotyped retroviral vectors target gene transfer to CD4-positive T cells...
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