Article
Detection of cytokines at the site of tuberculin-induced delayed-type hypersensitivity in man.
Clinical and experimental immunology - 1 Dec 1992
Chu C Q, Field M, Andrew E, Haskard D, Feldmann M, Maini R N
Abstract excerpt
Cytokines are chiefly local mediators which play an important role in the regulation of the cell-cell interactions which may be involved in the development of the delayed-type hypersensitivity (DTH) reaction. Using immunohistochemical techniques, the presence of IL-1 alpha, IL-1 beta, IL-6, interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) in the skin in tuberculin-purified protein...
Topics
- B-Lymphocytes
- Cytokines
- HLA-DR Antigens
- Humans
- Hypersensitivity, Delayed
- Immunohistochemistry
- Interferon-gamma
- Interleukin-1
- Interleukin-6
- Kinetics
- Langerhans Cells