Article
Ferredoxin reductase: pharmacogenomic assessment in colorectal cancer.
Cancer research - 1 Oct 2003
Yu Jinsheng, Marsh Sharon, Ahluwalia Ranjeet, McLeod Howard L
Abstract excerpt
Ferredoxin reductase (FDXR) is a putative contributor to TP53-mediated apoptosis from 5-fluorouracil chemotherapy through the generation of oxidative stress. With TaqMan real-time quantitative reverse transcription-PCR, this study established a significant difference in FDXR relative RNA expression level between tumor (median, 212.9 units) and normal tissues (median, 113.8 units) from 51 colorectal cancer...
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