Article
Long-term psychological impact of carrying a BRCA1/2 mutation and prophylactic surgery: a 5-year follow-up study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 15 Oct 2003
van Oostrom Iris, Meijers-Heijboer Hanne, Lodder Litanja N, Duivenvoorden Hugo J, van Gool Arthur R, Seynaeve Caroline, van der Meer Conny A, Klijn Jan G M, van Geel Bert N, Burger Curt W, Wladimiroff Juriy W, Tibben Aad
Abstract excerpt
PURPOSE: To explore long-term psychosocial consequences of carrying a BRCA1/2 mutation and to identify possible risk factors for long-term psychological distress. PATIENTS AND METHODS: Five years after genetic test disclosure, 65 female participants (23 carriers, 42 noncarriers) of our psychological follow-up study completed a questionnaire and 51 participants were interviewed. We assessed general and hereditary...
Topics
- Adult
- Anxiety
- Body Image
- Depression
- Female
- Genes, BRCA1
- Genes, BRCA2
- Genetic Carrier Screening
- Genetic Predisposition to Disease
- Genetic Testing
- Humans
- Mastectomy