Article
Mutant yolk proteins lead to female sterility in Drosophila.
Developmental biology - 1 Nov 1992
Butterworth F M, Burde V S, Bownes M
Abstract excerpt
Specific mutations in the yolk protein genes, yp1 and yp2, of Drosophila melanogaster cause the yolk proteins (YPs) they encode to precipitate, ultimately resulting in female sterility. YPs of the yp1 mutant fs(1)1163 are secreted normally but then precipitate as globules and occasionally as crystalline fibers in the subbasement membrane space of the fat body (Butterworth et al., 1991, J. Cell Biol. 112,...
Topics
- Animals
- Cell Membrane
- Drosophila melanogaster
- Egg Proteins
- Endocytosis
- Female
- Genotype
- Infertility
- Oocytes
