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Article

Cystic fibrosis carrier testing in an ethnically diverse US population.

Clinical chemistry - 1 Jun 2011

Rohlfs Elizabeth M, Zhou Zhaoqing, Heim Ruth A, Nagan Narasimhan, Rosenblum Lynne S, Flynn Kerry, Scholl Thomas, Akmaev Viatcheslav R, Sirko-Osadsa D Alexa, Allitto Bernice A, Sugarman Elaine A

Abstract excerpt

BACKGROUND: The incidence of cystic fibrosis (CF) and the frequency of specific disease-causing mutations vary among populations. Affected individuals experience a range of serious clinical consequences, notably lung and pancreatic disease, which are only partially dependent on genotype. METHODS: An allele-specific primer-extension reaction, liquid-phase hybridization to a bead array, and subsequent fluorescence...

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Source

Identifiers

PMID: 21474639
DOI: 10.1373/clinchem.2010.159285

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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