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Article

Isolation and synthesis of a new bio-antimutagen, petasiphenol, from scapes of Petasites japonicum.

Bioscience, biotechnology, and biochemistry - 1 Nov 1992

Iriye R, Furukawa K, Nishida R, Kim C, Fukami H

Abstract excerpt

A new bio-antimutagen, petasiphenol [3-(3,4-dihydroxyphenyl)-2-oxopropyl caffeate] (1) was isolated from scapes of Petasites japonicum (AD50 = 95 micrograms/ml against UV-induced mutagenic E. coli WP2 B/r Trp-. Petasiphenol (1) and its isomer (2) were synthesized. The activity of 1 was observed in the presence of soybean oil (glyceride), although the isomer (2) did not show any activity in doses up to 300...

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PMID: 1369070
DOI: 10.1271/bbb.56.1773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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